Bence Olveczky, Ph.D.
Department of Organismic and Evolutionary Biology
Center for Brain Science
I will introduce a new motor skill learning paradigm that trains stereotyped complex motor sequences in rodents. Targeted lesions show that motor cortex is essential for learning these skills, but not for executing them, thus dissociating motor cortex's role in motor learning and control. Neural recordings from motor cortex-recipient striatum (dorsolateral striatum, DLS) revealed that DLS neurons encode the learned skills in a sparse, reliable, and premotor manner, indicative of a causal role in skill execution. Consistent with this, lesions to DLS interfered both with motor skill learning and execution, while selective ablation of motor cortical inputs to the striatum abolished learning. Taken together, these results suggest that motor cortex guides plasticity in striatum during skill learning, allowing subcortical motor circuits to acquire and autonomously execute motor skills.
Coffee and snacks are served at 4:00 P.M. in Scott Hall BME kitchen area, where students may meet the speaker.
August 25-26 2018
September 17-19 2018
Westin Buckhead Hotel, Atlanta, GA
September 19-22 2018
Integrated Innovation Institute
2018 ACM Richard Tapia Celebration of Diversity in Computing
Hyatt Regency Orlando, Orlando, FL
September 26-28 2018
George R. Brown Convention Center, Houston, TX
October 2-5 2018
October 8 2018
12:00 PM - 1:20 PM
Scott Institute for Energy Innovation
Feedback, fast and slow: A field study on activity-specific feedback on energy consumption
Hamburg Hall A301