Alik Widge, MD, Ph.D.
Director, Translational NeuroEngineering Lab
Division of Neurotherapeutics
Massachusetts General Hospital
Mental disorders are arguably the largest public health problem of our age. They are the largest cause of disability worldwide, and yet current treatments work poorly for most patients. Neuroscience increasingly suggests that mental disorders arise from dysfunction in specific brain circuits, but medication and talk therapy do not target those circuits. More recently, multiple groups have used implantable systems (deep brain stimulators, DBS) to electrically stimulate those circuits. DBS had strong initial promise, but large-scale clinical trials had poor outcomes. A key cause of that failure is that all prior investigations have been open-loop, delivering energy without measuring how or whether the brain changes in response. By shifting to closed-loop approaches, we could better identify which patients should receive DBS and what stimulation patterns might produce
Coffee and snacks are served at 4:00 P.M. in Scott Hall BME kitchen area, where students may meet the speaker.
July 25 2018
11:00 AM - 12:30 PM
Electrical and Computer Engineering
Summer undergraduate internship research symposium
Scott Hall, Marquis Room