Nanotechnology Lab

The main focus of research in her laboratory has been the development of chiral NPs for enantioselective chemical processing. Chiral NPs have atomic structures with a specific “handedness” that allows them to discriminate between the handedness of complex chemicals such as biomolecules and pharmaceuticals. Enantioselective production of chiral chemicals requires the use of chiral media such as chiral catalysts.

Nisha Shukla

Nisha Shukla

Research Faculty, Engineering Research Accelerator

Nisha Shukla is a research faculty member with Engineering Research Accelerator and courtesy appointment in the Department of Chemical Engineering in the College of Engineering at Carnegie Mellon University. Her research interests are focused on nanomaterials, nanotechnology applications in pharmaceuticals, catalysis, disk drives, and quantum dots.

6117 Scott Hall; Lab: 1203 Doherty Hall

Current projects


  1. Nisha Shukla, Timothy John Klemmer, Dieter Klaus Weller, Chao Liu, “Method of producing self-assembled cubic FePt nanoparticles and apparatus using same ”. US Patent Number 8383254B2, issued Feb 26, 2013.
  2. Nisha Shukla , Timothy John Klemmer, Dieter Klaus Weller, Chao Liu , “Method of producing self-assembled cubic FePt nanoparticles and apparatus using same”. US Patent Number 7807217, issued Oct 5, 2010.
  3. Nisha Shukla, Joachim Ahner and Dieter Weller, “Mass storage apparatus using fluorine mediated self-assembly monolayers of nanoparticles recording medium” US Patent Number 7638211, issued Dec 9, 2009.
  4. Dieter Weller, Niel Deeman, Rene van de Veerdonk, Nisha Shukla “Magnetic Recording Media Having Self-organized Magnetic Arrays” US Patent Number 7,041,394, issued May 9, 2006.
  5. Dimitri Litvinov, Nisha Shukla, Erik B. Svedberg, Sakhrat Khizroev, Dieter K. Weller, “Selective annealing of magnetic recording films,” US Patent Number 6,884,328, issued April 26, 2005.
  6. Sakhrat Khizroev, Dimitri Litvinov, Nisha Shukla, Roy Gustafson “Perpendicular Reader with a Differentiating Shield” US Patent Number 6,738,233, issued May 18, 2004.
  7. Joachim Ahner, Nisha Shukla and Dieter Weller, “Nanoscale reactor for high pressure and high temperature chemical reactions and chemical ordering” US patent application number 20060099452 submitted in Oct 2004.
  8. Nisha Shukla, Raj Thangaraj, Mike Stirniman, Jing Gui “Magnetic Recording Media containing a Lubricant Layer with Enhanced Corrosion Performance” US patent application number 20020119316, filed Aug. 29, 2002.

Important publications

  1. Shukla N. and Gellman A.J., “Chiral metal surfaces for enantioselective processes” Nature Materials, 2020, 19, 939.
  2. Shukla N. Blonders Z. and Gellman A.J., “Chiral separation of rac-propylene oxide on  penicillamine coated gold NPs”, Nanomaterials, 2020, 10, 1716.
  3. Shukla N., Yang D., Gellman A.J., “Enantiomeric separations of chiral pharmaceuticals using chirally modified tetrahexahedral Au nanoparticles”, Surf. Sci. Vol. 648, 2016, Special Issue, 29.
  4. Shukla N., Ondeck N., Khosla N., Petti A.,Gellman A.J, “ Polarimetric Detection of Enantioselective Adsorption by Chiral Au Nanoparticles - Effects of Temperature, Wavelength and Size”, Nano materials and Nanotechnology, 5, 2015 , 1.
  5. Shukla N., Ondeck N., Gellman A.J., “Quantitation of enantiospecific adsorption on chiral nanoparticles from optical rotation”, Surf Sci. Vol. 629, 2014, Special Issue, 15.
  6. Shukla N., Nigra M. M and Gellman A.J., “One-step synthesis process for alloy ternary quantum dots”  Nano-micro lett. Vol. 4 (1), 2012, 52.
  7. Shukla N., Ondeck A., Lee J.C.,  Miller J.B.,“ NiFe2O4@SiO2 Nanoparticles Stabilized by Porous Silica Shells”, Catalysis lett. , Vol. 142 (5), 2012, 582.
  8. Shukla N., Miller J.B, Coletta E., A. Ondeck, Pushkarev V. and Gellman A.J., “Synthesis of  Nanorods with Ni cores and porous silica coatings”, Catalysis Lett. 141, 2011, 491.
  9. Shukla N., Bartel M. A, A.J. Gellman A.J. “Enantioselective separations on chiral Au nanoparticles” Am.Chem.Soc., 132 (25), 2010, 8575.
  10. Gellman A.J. and Shukla N., “Nanocataylis: More than Speed”, Nature Materials, Vol.8, No.2, 2009, 87.
  11. Matyjaszewski K., Miller P. J., Shukla N., Immaraporn B., Gellman A.J., Luokala B. B., Siclovan T. M., Kickelbick G., Vallant T., Hoffmann H., and Pakula T., “Polymers at Interfaces:  Using Atom Transfer Radical Polymerization in the Controlled Growth of Homopolymers and Block Copolymers from Silicon Surfaces in the Absence of Untethered Sacrificial Initiator” Macromolecules, 1999, 32, 26, 8716.

Professional spotlights

Feature story:  Carnegie Mellon University, Engineering Magazine, “Nanotechnology—Engineering Better Health,” January 2012.

JACS article: “Enantioselective separations using chiral Au nanoparticles” (2010-2011)

Media coverage

Editorial BoardNanotechnology, Science and Applications - Dove Press

Media mentions

CMU Engineering

Research offers experience to undergraduate students

Engineering students at Carnegie Mellon are often involved in research labs with faculty, post-doctoral researchers, and graduate students. But Marcus Yu had the unique experience of working in a lab that included researchers who were entirely undergraduate students.

CMU Engineering

Foundation for the future

Zachary Blonder’s experience conducting research on processes relevant to pharmaceuticals synthesis with Nisha Shukla as an undergraduate steered him toward a position in the pharma industry after graduation.

CMU Engineering

Discovery of naturally chiral surfaces for safer pharmaceuticals

Nisha Shukla and Andrew Gellman have developed a number of new, easier methods for making naturally chiral metal surfaces.