Daniel Cohen, Ph.D.
Life Science Research Foundation Fellow
Department of Biology
Biological tissues can be regarded as communal, active materials whose form and function derive directly from the collective behaviors of the myriad cells that comprise them. An interdisciplinary approach—drawn from control theory, fluid mechanics, materials science, and swarm theory—has afforded us an unprecedented view of the mechanics underlying such collective systems. My work posits that understanding such collective cell behaviors should allow us to control them, just as a shepherd understands how to use sheepdogs to control a flock of sheep. This is especially exciting in the context of tissues, where new engineering rules and tools premised upon collective behaviors will help us address growing challenges in both biomechanics research and biomedical technology development.
I will present two, complimentary examples of such collective engineering—Outside-In and Inside-Out control. Outside-In control relies on external control cues to guide collective behavior, an example of which is my work to remotely herd collective cell migration using programmable, bioelectric cues and living tissues. By contrast, Inside-Out control relies on the “wolf-in-sheep’s-clothing” motif, where I have created a micro-fabricated biomaterial that can trick surrounding cells into interacting with it as if it, too, were a cell. Building on these examples, I will present a vision of how understanding collective mechanics and developing collective engineering approaches will enable us to better engineer tissues and future materials.
Coffee and snacks are served at 4:00 P.M. in Scott Hall BME kitchen area, where students may meet the speaker.
September 17-19 2018
Westin Buckhead Hotel, Atlanta, GA
September 19-22 2018
Integrated Innovation Institute
2018 ACM Richard Tapia Celebration of Diversity in Computing
Hyatt Regency Orlando, Orlando, FL
September 26-28 2018
George R. Brown Convention Center, Houston, TX
October 2-5 2018
October 8 2018
12:00 PM - 1:20 PM
Scott Institute for Energy Innovation
Feedback, fast and slow: A field study on activity-specific feedback on energy consumption
Hamburg Hall A301
October 23-25 2018
Information Networking Institute
Executive Women's Forum 2018 National Conference
Hyatt Regency, Scottsdale, AZ